On Monday, March 16, at 18:30 EET we are delighted to host our guests Dr. Bogdan Mirăuță who will present latest research about the #resistome and #microbiome-immune interactions under treatment pressure.

Talk: 

Dr. Bogdan Mirăuță, "The resistome and microbiome–immune interactions in a cohort from Romania", Romanian Bioinformatics Cluster, Romania

Abstract. The intestinal microbiome plays an essential role in host health, influencing various functions of the body. A balanced microbiome is associated with favorable health states; however, excessive use of antibiotics and diet can lead to dysbiosis, affecting the body’s homeostasis. In this talk, I will present the metagenomic analysis of the intestinal microbiome in a healthy cohort from Romania, a population characterized by high antibiotic consumption. The study contributes to uncovering microbial diversity in Europe, providing insights into community configurations and correlations with existing enterotype models. I will also discuss the analysis of antimicrobial resistance and the correlations observed between the prevalence of resistance genes and antibiotic consumption within the population. Finally, I will present results regarding the relationship between the microbial profile and systemic immune responses, identifying a possible link between the Prevotella enterotype and the balance of cytokine production.

Resources:

• Bogdan Mirăuță, bioRxiv, "Resistome and microbiome-immune interactions in an Eastern European population with high antibiotic use", https://www.biorxiv.org/content/10.64898/2026.01.22.700835v2

Format: Online, free to attend, registration required: zoom

Organization: YMS is organized by RSBI and is linked to RoBioinfo Seminars

Chair: Marius Surleac

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